In 2025, non-invasive vagus nerve stimulation (VNS) has transitioned from a clinical treatment to a mainstream wellness tool, with a growing market of wearable devices designed for home use. These devices deliver gentle electrical or vibrational pulses through the neck, wrist, or ear to stimulate the vagus nerve, a key regulator of the parasympathetic nervous system responsible for relaxation, digestion, and heart rate.
Research supports their use for several conditions. Clinical studies and reviews, including those cited by device manufacturers and in journals like Frontiers in Neuroscience, show VNS can significantly reduce the frequency and severity of migraines and help manage symptoms of treatment-resistant depression and anxiety by promoting neuroplasticity and balancing stress hormones. A primary, measurable benefit is the improvement in Heart Rate Variability (HRV), a key marker of resilience and autonomic nervous system health.
The market is now competitive, with top-rated devices like the Pulsetto neck collar and the Truvaga Plus handheld unit leading consumer reviews for affordability and ease of use. The field received a significant boost in 2025 with news of clinical trials demonstrating VNS's remarkable efficacy when combined with therapy for treatment-resistant PTSD. Furthermore, regulatory bodies like the FDA have continued to expand approvals for VNS technologies, solidifying their role in managing chronic conditions.