The Trump Administration unveiled over $5 billion in federal commitments on Tuesday to expand the Genesis Mission, a national effort to use artificial intelligence to accelerate scientific discovery across more than 15 government agencies.
Launched by executive order in November 2025 under the Department of Energy, the programme has now been expanded into a whole-of-government initiative. The Energy Department will open its 17 national laboratories to participating researchers and provide access to the American Science and Security Platform, a shared infrastructure connecting scientists with datasets, computing power, and AI tools. Two hundred and seventy-eight research projects have been selected in the first round, according to Energy Secretary Chris Wright.
Microsoft is investing $60 million and contributing alongside academic institutions and AI firms including OpenAI and Anthropic. The Department of Health and Human Services will use the platform to pursue AI-driven biomedical research, with NIH Director Jay Bhattacharya saying patients with cancer, chronic disease, and rare conditions "cannot afford to wait decades" for discoveries to reach them. The programme also spans transportation, interior, and national security applications.
Michael Kratsios, director of the White House Office of Science and Technology Policy, framed the Genesis Mission as the latest in a tradition of national scientific mobilisations. "America's greatest scientific achievements have been born of national mobilizations paired with the construction of new institutions," he said. A summit coinciding with the announcement is being held today in Washington.