Discovery could improve learning speed by tuning into your brainwaves

Delivering information at the natural tempo of your neural pulses could accelerate your ability to learn, University of Cambridge neuroscientists have discovered.

They used EEG brain sensors attached to the head to measure participants’ alpha brain waves (8 to 13 Hz). The researchers then used these readings to create a 1.5-second optical “pulse”: a white square flickering on a dark background at the same tempo as each person’s individual alpha waves.

The mid-range of the brainwave spectrum, the alpha frequency range, tends to dominate when we are awake and relaxed.

Three times faster in a cognitive task

Participants who received this visual cue (or “entrainment”) at their personal brainwave frequency were at least three times faster in improving at a cognitive task (trying to identify specific shapes within a barrage of visual clutter). The improvement persisted the next day.

Priming brains for optimal rhythms could help us remain quick learners (with “neuroplasticity”) throughout life, help people with learning difficulties, and give professionals an edge in training simulations, the neuroscientists suggest.

EEG headband kit
(credit: OpenBCI)

Their study used complex EEG machines, but there are simple headband systems that could allow you to measure brain frequencies quite easily, say the researchers. As Tim Cook would say, “We can’t wait to see what you’ll discover!”

Meanwhile, the findings will be explored as part of the Centre for Lifelong Learning and Individualised Cognition: a research collaboration between Cambridge and Nanyang Technological University (NTU), Singapore.  

How it works

A brainwave cycle consists of a peak and trough. Some participants received pulses matching the peak of their waves, some the trough, while some got rhythms that were either random or at the wrong rate (a little faster or slower). Each participant repeated over 800 variations of the cognitive task, and the neuroscientists measured how quickly people improved.

When participants returned the next day to complete another round of tasks, those who learned much faster under entrainment had maintained their higher performance level. 

“It was exciting to uncover the specific conditions you need to get this impressive boost in learning,” said first author Dr. Elizabeth Michael, now at Cambridge’s Cognition and Brain Sciences Unit. “The intervention itself is very simple, just a brief flicker on a screen, but when we hit the right frequency plus the right phase alignment, it seems to have a strong and lasting effect.”

Importantly, entrainment pulses need to synch with the trough of a brainwave. Scientists believe this is the point in a cycle when neurons are in a state of “high receptivity.”

Wide range of potential uses

“We are tapping into a mechanism that allows our brain to align to temporal stimuli in our environment, especially communicative cues like speech, gaze and gesture that are naturally exchanged during interactions between parents and babies,” said aid co-author Prof Victoria Leong, from NTU and Cambridge’s Department of Paediatrics.  

“When adults speak to young children they adopt child-directed speech – a slow and exaggerated form of speaking. This study suggests that child-directed speech may be a spontaneous way of rate-matching and entraining the slower brainwaves of children to support learning.”

The researchers note that while the new study tested visual perception, these mechanisms are likely to be “domain general,” applying to a wide range of tasks and situations, including auditory learning. Other early applications of brainwave entrainment to boost learning could involve training in professions where fast learning and quick decision-making is vital, such as pilots or surgeons.

“Our brain’s plasticity is the ability to restructure and learn new things, continually building on previous patterns of neuronal interactions. By harnessing brainwave rhythms, it may be possible to enhance flexible learning across the lifespan, from infancy to older adulthood,” Kourtzi said.

The findings, published in the journal Cerebral Cortex, will be explored as part of the Centre for Lifelong Learning and Individualised Cognition, a research collaboration between Cambridge and Nanyang Technological University (NTU), Singapore.  

“We feel as if we constantly attend to the world, but in fact our brains take rapid snapshots and then our neurons communicate with each other to string the information together,” said co-author Prof Victoria Leong, from NTU and Cambridge’s Department of Paediatrics.  

“Our hypothesis is that by matching information delivery to the optimal phase of a brainwave, we maximize information capture because this is when our neurons are at the height of excitability.”

Starts with mother/baby communication

Previous work from Leong’s Baby-LINC lab shows that brainwaves of mothers and babies will synchronize when they communicate. Leong believes the mechanism in this latest study is so effective because it mirrors the way we learn as infants.  

“We are tapping into a mechanism that allows our brain to align to temporal stimuli in our environment, especially communicative cues like speech, gaze and gesture that are naturally exchanged during interactions between parents and babies,” said Leong.

“When adults speak to young children they adopt child-directed speech — a slow and exaggerated form of speaking. This study suggests that child-directed speech may be a spontaneous way of rate-matching and entraining the slower brainwaves of children to support learning.”

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AI Startup Anthropic Close to Securing $5 Billion Valuation with New Funding Round

Anthropic, an artificial intelligence startup, is making waves in the tech industry with its latest funding round. The San Francisco-based company is on the verge of securing a $300 million investment, which could value it at $5 billion. Anthropic has been on a mission to make systems easier to control and understand through its research on machine learning systems since its inception in 2021. The new funding will allow the company to delve deeper into AI’s predictable scaling properties and investigate how capabilities and safety issues can emerge. The success of the startup demonstrates the ongoing excitement for the new class of AI startups as well as Silicon Valley’s continued focus on generative AI. Anthropic is a shining example of a ray of hope in an otherwise bleak tech investment market.

From their CEO & Cofounder, Dario Amodei:

“With this fundraise, we’re going to explore the predictable scaling properties of machine learning systems, while closely examining the unpredictable ways in which capabilities and safety issues can emerge at scale”

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Microsoft Confirms Its $10 Billion Investment Into ChatGPT, Changing How Microsoft Competes With Google, Apple And Other Tech Giants

Microsoft’s recent investment in OpenAI, the company behind the AI-powered chatbot ChatGPT, is a strategic move that places the tech behemoth at the cutting edge of generative artificial intelligence. The $10 billion investment will power the workloads of research, products, and API services, as well as extend Microsoft’s partnership with OpenAI. Microsoft Azure will continue to be the startup’s sole cloud provider, despite its $29 billion valuation. This investment comes at a time when Microsoft is cutting 10,000 jobs globally while also investing heavily in AI-based technology. The AI-powered chatbot, which already has one million users after only a few months, has the potential to change the AI landscape and be the “iPhone moment” for the field.

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Google is testing a new AI model called MusicLM, which can generate “high-fidelity music from text descriptions”.

Google’s new artificial intelligence system, MusicLM, can compose music in any genre based on a written description. This system is one of a kind because of its capacity to produce high-quality, cohesive music that is both highly complex and capable of building on preexisting tunes. MusicLM can also create tunes based on specific parameters such as location, time period, and mood. For the purpose of learning to create music, the system was exposed to a whopping total of 280,000 hours of music throughout its training phase. Some of the system’s samples are distorted, and there are problems with the created vocals, despite its amazing capabilities. Ethical issues, such as the possible infringement of copyright, were also brought up by the researchers.

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Generative AI like viral ChatGPT lands on DISA technology watch list

Defense Information Systems Agency (DISA) authorities in the United States have taken note of ChatGPT, a bot developed by OpenAI that generates natural-sounding material using AI. DISA’s watch list, which is frequently updated to include areas that have become critical to defense connectivity and security, now include ChatGPT. The U.S. military has been investing in artificial intelligence and related technologies to enhance battlefield analysis and maintenance forecast, although the precise application of generative AI in the Pentagon yet to be seen. From $600 million in 2016, public investment in AI at the Pentagon has climbed to $2.5 billion in 2021, and by early 2021, more than 685 AI projects had been initiated. While ChatGPT has the potential to increase efficiency in the workplace, it is not without its critics who raise concerns about potential prejudice and ethical issues.

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Watch Out, Software Engineers: ChatGPT Is Now Finding, Fixing Bugs in Code

According to a new study by computer science researchers from Johannes Gutenberg University Mainz and University College London, OpenAI’s ChatGPT outperformed existing AI systems in fixing software bugs. ChatGPT solved 31 of 40 problems with buggy code, while Codex, CoCoNut, and Standard APR solved 19, 19, and 7 problems, respectively. ChatGPT’s main advantage is its ability to converse with humans, allowing it to request more information and increase its success rate. The research has the potential to upend the $600 million bug-fixing software industry. However, because ChatGPT is a public database, it may be difficult for tech companies to adopt it in its current form. The impact of ChatGPT on software development in the future remains to be seen.

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How Google’s AI tool Sparrow is looking to kill ChatGPT

Sparrow AI is a new language model developed by Google that could potentially replace existing tools such as ChatGPT. The ability of Sparrow to understand context and perform multiple NLP tasks with a single model is its key advantage. This increases its versatility and efficiency over ChatGPT, which is primarily used for text generation and language modeling. Sparrow has the potential to become a popular choice in the near future due to its efficient training and improved safety features. It is important to note, however, that there may be biases and political battles over its sources and how it links to information. Sparrow, on the other hand, is a powerful tool with improved NLP capabilities that is worth keeping an eye on as it is set to be released for limited testing in 2023.

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The search for a habitable Earth 2.0

In about 5 billion years, the Sun is due to turn into a red giant. But long before then, there are other concerns, such as asteroids, global warming, and nuclear destruction.

So there’s a long-range quest to find planets that orbit stars other than the Sun, referred to as “Earth 2.0.” As conceived by NASA, Earth 2.0 would be a habitable planet similar enough to Earth , intended to enable the existence of life as we know it. Assuming we could somehow get there, we would also require a “habitable zone” that:

  • Is similar enough to Earth to enable existence of life as we know it.
  • Is the right temperature for liquid water
  • Orbits a nearby star with a steady supply of light.
  • Ideally, is close enough that we could imagine going there or at least sending a probe to explore it.

Researchers at Rensselaer Polytechnic Institute have just received a grant from NASA to find out how. Or at least, find all such habitable-zone planets closer than 10 parsecs, or 192 trillion miles, the range of our technology. The researchers are leading a team in pursuit of an idea that could make it possible to find nearby, habitable, Earth-like planets — or prove that they are unlikely to exist.

Heidi Jo Newberg, professor of physics, applied physics, and astronomy at Rensselaer, has been named a NASA Innovative Advanced Concepts (NIAC) Program Fellow. She will join a prestigious group of innovative scientists whose visionary ideas have included new types of space propulsion systems, robots that are modeled after nature such as spiderbots, and technology that makes it easier for humans to live in space.

Three times the diameter of the James Webb Space Telescope — range: 192 trillion miles

“Dittoscope” ("Diffractive Interference Coronagraph Exoplanet Resolver") (or DICER) telescope,
The DICER telescope could find all habitable zone planets closer than 192 trillion miles (credit: Rensselaer Polytechnic Institute)

The key technology, designed by Thomas D. Ditto, inventor of the “Dittoscope” (“Diffractive Interference Coronagraph Exoplanet Resolver” or DICER) telescope, would be three times the diameter of the state-of-the-art James Webb Space Telescope. It’s designed to find all habitable zone planets closer than 10 parsecs, or 192 trillion miles.

Thomas Ditto, inventor of the Dittoscope (DICER)

“With DICER, light from a faint planet would be collected by two 10-meter diffraction gratings, which are easier to pack up in a rocket to shoot into space than a telescope with conventional mirrors and lenses,” Ditto explained. “DICER uses a diffraction grating primary objective and that changes everything.”

To determine whether conditions on a planet are right for life or whether it has already started to develop, scientists look at the air that surrounds the planet. But DICER may even be able to detect if the newly discovered exoplanets have atmospheric ozone, a biomarker that may indicate the existence of life as we know it.

Is all this feasible?

“Nobody really knows,” Newberg says. “We could find zero or we could find 100 habitable exoplanets. But the discovery of even one oxygen-rich, terrestrial exoplanet in the local neighborhood of our own Sun would be among the most publicly engaging astronomical results of all time!

“The DICER technology is also scalable, so the potential exists to find exoplanets that are fainter or farther away in the future. So far, most exoplanets have been found because they pass in front of their host star and block some of its light, but DICER could find exoplanets that orbit in any orientation.”

Newberg and her doctoral student Leaf Swordy will collaborate with Shawn Domagal-Goldman and Richard K. Barry, astronomers at NASA Goddard Space Flight Center; and L and Frank Ravizza, optical engineers at Lawrence Livermore National Laboratory.

Update January 31:

Comments by legendary science-fiction author and astronomer Dr. David Brin sent to Mindplex

I doubt NASA wants to be directly cited as fostering notions of interstellar colonization.

1. Because of the distances … the nearest such world (if they exist at all) … would be a million times farther than NASA’s greatest current ambition.

2. A popular expression is “there is no Planet B.” If you talk about a backup world to Earth, you risk being denounced as someone willing to give up on saving Planet A.

I’d rewrite the opening to emphasize that.

While it is both fun and enthralling to speculate about our descendants someday crossing the vast interstellar gulfs to other habitable worlds, that is not the central goal of scientific campaigns to seek “Earthlike planets” out there.  No such world can ever serve as a “Planet B” to escape from our duties, here in the Solar System. Still NASA and the European Space Agency and others have prioritized the search for life-bearing worlds circling other stars, in part because of great public and scientific interest. But another motive must be to gain information about alien ecosystems — both their similarities and differences — which might improve our models and our planetary management, here at home.

David Brin

www.davidbrin.com

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Got insomnia? You may want to listen to your brain with an ‘acoustic mirror’

A good night’s sleep is crucial to health and wellbeing. Numerous research studies have shown that insomnia can increase the risk of cardiovascular events, obesity, diabetes and other illnesses. 

Now a new study by researchers at Wake Forest University School of Medicine has shown significant improvements in both sleep quality and improved autonomic nervous system function, using closed-loop, acoustic-stimulation neurotechnology.

How to listen to your brain

Invented by Scottsdale, Arizona-based Cereset, the idea is to monitor your brainwaves using EEG scalp sensors, then use software algorithms to translate specific brain frequencies into audible tones of varying pitch*. These tones, synchronized with the brain waves, are echoed back in real time via earbuds. In effect, this lets your brain listen to itself.

This “Cereset Research with Standard Operating Procedures” (CR-SOP) method (an improvement to HIRREM) “allows the brain to reset from stress patterns that contribute to insomnia, says Charles H. Tegeler, M.D., chair of neurology at Wake Forest University School of Medicine. “During the intervention, the brain continuously updates with respect to its own activity patterns, resulting in auto-calibration or self-optimization,” he explained.

Clinically significant improvements

To assess this method, Tegeler led a new study, published in Global Advances in Integrative Medicine and Health, an open-access journal.

In a randomized and controlled study of 22 adults, researchers compared changes on the Insomnia Severity Index (ISI), a self-report instrument to assess insomnia symptoms. Subjects in the CR-SOP group reported reduced insomnia symptoms. They also showed statistically and clinically significant improvements in autonomic function across multiple measures such as heart rate variability (HRV) and baroreflex sensitivity (BRS), compared to those who received random tones.

The core brain-mirroring technology is now available in 58 local Cereset client centers in the US, according to the company. Hopefully, this ingenious tech can help stressed-out folks, such as Covid healthcare workers and caregivers.

* Hmmm, could this allow for creating music with your mind? (Paging Jam Galaxy!)

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Anti-aging gene shown to rewind heart age by 10 years in centenarians

Single administration halts decay

An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart’s biological age by 10 years, offering a potential target for patients with heart failure.

The gene was discovered by scientists at the University of Bristol and the MultiMedica Group in Italy, and funded by the British Heart Foundation and the Italian Ministry of Health. The study was published in the journal Cardiovascular Research.

Carriers of healthy mutant genes, like those living in blue zones of the planet, often live to 100 years or more and remain in good health. These individuals are also less prone to cardiovascular complications. Scientists believe the gene helps to keep their hearts young by protecting them against diseases linked to aging, such as heart failure.

In this new study, researchers demonstrate that one of these healthy mutant genes, previously proved particularly frequent in centenarians, can protect cells collected from patients with heart failure requiring cardiac transplantation.

Single administration halts decay of heart function in elderly mice

The Bristol team, led by Professor Paolo Madeddu, has found that a single administration of the mutant anti-aging gene halted the decay of heart function in middle-age mice. Even more remarkably, when given to elderly mice, whose hearts exhibit the same alterations observed in elderly patients, the gene rewound the heart’s biological clock age by the human equivalent of more than ten years.

Professor Madeddu, Professor of Experimental Cardiovascular Medicine from Bristol Heart Institute at the University of Bristol and one of the study’s authors, explained: “The heart and blood vessel function is put at stake as we age. However, the rate at which these harmful changes occur is different among people. Smoking, alcohol, and sedentary life make the aging clock faster. Whereas eating well and exercising delay the heart’s aging clock.

Healthy gene found in centenarians could be transferred to unrelated people to protect their hearts

“In addition, having good genes inherited from parents can help to stay young and healthy. Genes are sequences of letters that encode proteins. By chance, some of these letters can mutate. Most of these mutations are insignificant; in a few cases, however, the mutation can make the gene function worse or better, like for the mutant anti-aging gene we have studied here on human cells and older mice.”

Monica Cattaneo, a researcher of the MultiMedica Group in Milan, Italy, and first author of the work, said: “The cells of the elderly patients, in particular those that support the construction of new blood vessels, called ‘pericytes’, were found to be less performing and more aged. By adding the longevity gene/protein to the test tube, we observed a process of cardiac rejuvenation: the cardiac cells of elderly heart failure patients have resumed functioning properly, proving to be more efficient in building new blood vessels.”

Electron microscopy showed laminated bodies in pericytes about a capillary (Credit: Wikimedia Commons)

Centenarians pass their healthy genes to their offspring. The study demonstrates for the first time that a healthy gene found in centenarians could be transferred to unrelated people to protect their hearts. Other mutations might be found in the future with similar or even superior curative potential than the one investigated by this research. Professor Madeddu and Professor Annibale Puca of the MultiMedica Group believe this study may fuel a new wave of treatments inspired by the genetics of centenarians. 

Clinical trials

Professor Madeddu added: “Our findings confirm the healthy mutant gene can reverse the decline of heart performance in older people. We are now interested in determining if giving the protein instead of the gene can also work. Gene therapy is widely used to treat diseases caused by bad genes. However, a treatment based on a protein is safer and more viable than gene therapy.

“We have a new confirmation and enlargement of the therapeutic potential of the gene/protein, says Annibale Puca, Head of the laboratory at the IRCCS MultiMedica and Professor at the University of Salerno. “We hope to test its effectiveness soon in clinical trials on patients with heart failure.”

Paper: The longevity-associated BPIFB4 gene supports cardiac function and vascularization in aging cardiomyopathy by Annibale Puca et al. in Cardiovascular Research [open access]

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