CRISPR gene editing enters mainstream medicine as Casgevy approval fuels a clinical trial pipeline for cancer, rare diseases, and autoimmune conditions with FDA cutting red tape.

Scientists from Purdue and Columbia universities describe an RNA-guided molecular machine that activates gene expression by recruiting the cell’s transcription machinery, offering a gentler alternative to standard gene-cutting tools.

"NANITE" strategy amplifies genome editing in vivo by turning transfected cells into temporary factories that deliver Cas9 to their neighbors.

New technology from the University of Florida uses stable DNA guides to target RNA with greater precision and lower cost than traditional methods.

Scientists discover enzyme that cuts single-stranded DNA, opening doors to better gene editing and medical applications.