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Human genetics is reshaping drug discovery by revealing reliable targets, improving success rates, and reducing costly clinical failures in the development of safer, more effective treatments.

Google DeepMind has precomputed predicted effects for all nine billion possible single-letter DNA changes and released a simple score so researchers can look them up.

The new SuSiE² statistical framework integrates gene expression data directly into genetic fine mapping, allowing researchers to pinpoint true causal disease variants with unprecedented precision.

MIT engineers develop a compact system to regulate gene expression for safer, effective treatments of genetic disorders.