back Back

Fiber-infused ink enables 3D-printed artificial-heart muscles to beat

Jul. 31, 2023.
1 min. read 8 Interactions

Future plan: fabricate implantable tissues that can heal or replace faulty or diseased heart structure

About the writer

Amara Angelica

198.01421 MPXR

Amara Angelica is Senior Editor, Mindplex

3D-printed heart muscle beating through fiber-infused ink (credit: Harvard John A. Paulson) School of Engineering and Applied Sciences)

Scientists from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have invented artificial heart tissue that beats in coordination, like a human heart.

In a paper published in Nature Materials, the researchers report they have developed a new hydrogel ink infused with gelatin fibers and applied with “rotary jet-spinning.” This method allows muscle cells (printed in the shape of a ventricle) to align and beat in coordination, as in a human heart chamber.

Defeating heart disease with new implantable tissues

Initially, the 3D-printed cardiac tissues could help evaluate which treatments might work best in individual patients. But the future plan is to fabricate actual implantable tissues that can heal or replace faulty or diseased structures inside a patient’s heart, says Suji Choi, research associate at SEAS and first author on the paper.

Rotary Jet-Spinning (RJS) works like a cotton candy machine (credit: Harvard John A. Paulson School Of Engineering And Applied Sciences)

Citation: Choi, S., Lee, K. Y., Kim, S. L., MacQueen, L. A., Chang, H., Zimmerman, J. F., Jin, Q., Peters, M. M., Ardoña, H. A., Liu, X., Heiler, A., Gabardi, R., Richardson, C., Pu, W. T., Bausch, A. R., & Parker, K. K. (2023). Fibre-infused gel scaffolds guide cardiomyocyte alignment in 3D-printed ventricles. Nature Materials, 22(8), 1039-1046.

Let us know your thoughts! Sign up for a Mindplex account now, join our Telegram, or follow us on Twitter

Comment on this content


One thought on “Fiber-infused ink enables 3D-printed artificial-heart muscles to beat

  1. This groundbreaking research from the Harvard John A. Paulson School of Engineering and Applied Sciences represents a major stride towards combating heart disease. The invention of artificial heart tissue, capable of coordinated beating like a human heart, holds immense potential for personalized treatments and even implantable tissue replacements. A remarkable feat with promising implications for the future of cardiac care.
    1 Like







💯 💘 😍 🎉 👏
🟨 😴 😡 🤮 💩

Here is where you pick your favorite article of the month. An article that collected the highest number of picks is dubbed "People's Choice". Our editors have their pick, and so do you. Read some of our other articles before you decide and click this button; you can only select one article every month.

People's Choice